Acne vulgaris is a common disease characterized by 3 pathophysiologic processes: Presence of bacteria and subsequent inflammation, excess sebum production, excess keratinization. Recently, the involvement of the epidermal barrier has been emphasized.
Integration of skin barrier repair, represent a relevant strategy as a holistic approach in the management of acne. It may reduce the frequency and intensity of anti-acne-specific treatment side effects, improving patient adherence to drug treatment, and consequently, better clinical outcome
Atopic dermatitis (AD) could be considered as a barrier disease in which antigens and irritants that permeate the skin trigger and worsen the dermatitis. It has been speculated that the impaired barrier function of the skin in AD results from the decreased production of ceramides.
Taken together, the observed clinical efficacy of synthetic lipids, focusing on moisture replenishment and improving the ceramide profile, provides a deep insight into the pathogenesis of AD as a ceramide-deficient dise
Superficial Fungal Conditions
Superficial fungal infections are common at all ages, in both sexes, and have a worldwide distribution. These infections include tinea capitis, tinea cruris, tinea pedis, tinea corporis, tinea manuum, tinea barbae, tinea versicolor, and candidal infections are also common.
Treatment modalities include oral and topical agents. However, good personal hygiene is an important adjunct to antifungal therapy.
Hyperhidrosis, is sweating more than what is required for normal thermoregulation, it’s a condition that usually begins in either childhood or adolescence.
Although any site on the body can be affected, the sites most commonly involved are the palms, soles, and axillae. Severe cases of hyperhidrosis may adversely affect the patient’s quality of life.